Changes in Irisin, Interleukin-15 and Some Metabolic Parameters in Elderly Men with Metabolic Syndrome Following Increasingly Resistance Training

Background: The aging process is usually accompanied by a decrease in the function of the body's systems and physiological capacity, along with an increase in susceptibility to diseases, especially metabolic syndrome. This study looked at the effect of eight weeks of resistance training on levels of Irisin, IL-15, CRP, and Cholesterol in elderly men with metabolic syndrome. Methods: The statistical population was elderly men in Khorramabad, of whom 18 were selected and randomly divided into two experimental groups and control (65/2±2/2, 65/4±2/1). The exercise program included leg presses, chest presses, row movements, bending the knees, head, back of the arm, opening of the knees and front of the arm. The above program started with 30% of a maximum repetition and reached 50% of a maximum repetition at the end of the eighth week. Blood samples were taken 48 hours before and after the training sessions. Correlated t-test and independent t-test were used to examine the research data. The level of significance was also considered (P<0.05). Results: Eight weeks’ resistance exercise significant increase in Irisin (P=0.01) and interleukin-15 (P=0.007), as well as a significantly decreased levels of CRP (P=0.007) and total cholesterol(P=0.02) in elderly men with metabolic syndrome. Conclusion: Finding non-pharmacological solutions to improve metabolic indicators is very important. Based on the results of research, doing resistance exercises is recommended as a low-cost and non-pharmacological solution for the treatment of metabolic syndrome in elderly men.